Dimethicone
Dimethicone is a silicone-based polymer widely used in dermatology and skincare. As one of the most common moisturizing agents in modern formulations, it forms a lightweight, non-greasy barrier on the skin that helps retain moisture, smooth texture, and protect against environmental aggressors. It’s the second most used occlusive in moisturizers after petrolatum — and for good reason: it’s effective, versatile, and very well tolerated.
Though synthetic in origin, dimethicone is non-sensitizing and non-comedogenic (won’t clog pores), making it a popular choice in products for sensitive or acne-prone skin. It’s approved by the FDA as a skin protectant and often used in both medical and cosmetic-grade skincare.
When applied to the skin, Dimethicone creates an invisible, breathable film that offers multiple benefits:
Dimethicone’s benefits are especially valuable in treating or preventing dry, sensitive, or compromised skin. Here’s how it helps in common skin conditions:
In Metabase Cream, Dimethicone is one of the core barrier-protecting ingredients. It works synergistically with Urea, Panthenol, and Ceramides to deliver deep hydration and barrier support. While Urea and Panthenol draw in moisture and calm irritation, Dimethicone seals it in and helps shield the skin from dryness, cracking, and external irritants.
Its smooth, non-greasy feel makes Metabase Cream ideal for daily use, especially on areas prone to dryness and friction such as the hands, feet, elbows, and knees.